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胃液64-DP检测及其对胃癌的诊断意义

Detection of tumor marker (64-DP) in gastric juice by ELISA and its diagnostic value for gastric cancer
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摘要 本文采用酶联免疫吸附试验(ELISA)技术,建立了胃液64-DP的ELISA检测方法。经特异性抑制试验和重复性试验证明该方法特异性,敏感性和重复性均较好,而且操作简易快速。131例胃液标本测定结果显示,阳性率为84.6%(44/52);假阳性率为3.80%(3/79)。我们认为此法可作为胃癌普查和胃癌早期诊断的一种辅助手段。 The detection of DNA-binding protein 64-DP in gastric juice by ELISA using the double antibody sandwich method is presented. According to the results of inhibition and repetition test, this technique was shown to be specific, sensitive, relatively simple and rapid. 44 of 52 cases with gastric cancer were positive, with a positive rate of 84.6%. Only 2 out of 30 cases with benign gastric lesions showed positive. These results suggest that the detection of 64-DP in gastric juice might he of practical value in the dignosis of gastric cancer.
出处 《实用肿瘤杂志》 CAS 北大核心 1993年第4期207-209,共3页 Journal of Practical Oncology
关键词 胃液 64-DP 诊断 胃肿瘤 Tumor marker(64-DP) Gastric juice ELISA Gastric cancer Diagnosis
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