颅内肿瘤术中印片诊断价值和肿瘤细胞学特征的研究

The Value of Imprint Cytology in Diagnosis of Intracranial Tumors During Operation and Cytological Features of Intracranial Tumors

目的 评价颅内肿瘤手术中细胞学印片方法诊断的准确性。方法 15 0例颅内肿瘤在手术中经印片细胞学诊断 ,印片方法是送检标本免沾水 ,用吸水纸进一步吸干水分 ,清洁载玻片在标本上稍加用力压数下后 ,固定和HE染色。诊断时先观察印片 ,得出结果 ,将结果与冰冻切片结果和常规石蜡切片结果对照。结果 15 0例细胞学诊断结果表明其在非胶质肿瘤中良恶性判断准确率达 10 0 %,对肿瘤粗略分类的准确率达 91 3 %,对胶质瘤分级判断准确率达 88 3 %。此外 ,对胶质瘤、脑膜瘤和垂体腺瘤等常见肿瘤的印片细胞学形态作了简要的描述。结论 细胞学印片诊断准确率与冰冻切片接近 ,且两者有互补的作用。

Objective To evaluate the diagnostic accuracy of imprint cytology for intracranial tumors during operation. Methods 150 cases of intracranial tumors were diagnosed by imprint cytology. The imprint was prepared by touching the specimens several times with clean slide, and then the slides were fixed and stained with HE. The diagnostic results obtained by imprint cytology were compared with those made by frozen and routine paraffin sections. Results The accurant rates of diagnosing for non-glial tumors, classifying for incracranial tumors and grading for glial tumors were 100%, 91.3% and 88.3%, respectively. In addition, the morphological features of glial tumors, meningioma, pituitary adenoma on imprint cytology were briefly described. Conclusion The accurant rate of imprint cytology is almost equal to that of frozen section, and both the detection methods have a supplementary effect to each other.