无创正压通气治疗急性心源性肺水肿所致急性呼吸衰竭的疗效

The Clinical Efficacy Study of Non-invasive Positive Airway Pressure Ventilation in Acute Respiratory Failure for Acute Cardiogenic Pulmonary Edema

的 :探讨无创正压通气治疗急性心源性肺水肿所致急性呼吸衰竭的疗效。方法 :4 5例常规治疗无效的急性心源性肺水肿患者予无创正压通气治疗 ,观察治疗前后患者HR、RR、SBP、DBP和临床征象的变化 ,动脉血pH、PaO2 、PaCO2 、SaO2 的变化。结果 :无创正压通气治疗后 ,4 5例患者的临床症状明显改善 ,HR、RR、SBP、DBP和动脉血pH、PaO2 、PaCO2 、SaO2 等参数与治疗前比较均有极显著差异 (P <0 .0 1)。结论 :无创正压通气能迅速改善急性心源性肺水肿患者的临床症状和低氧血症 ,避免了气管插管 ,是抢救急性心源性肺水肿的一种安全有效的方法。

Objective:To explore the clinical effic acy of non-invasive positive airway pressure ventilation (NIPPV) in acute respirator y failure for acute cardiogenic pulmonary edema. Methods:45pa t ients with acute cardiogenic pulmonary edema(ACPE) who had no response to conven tional treatment were treated with NIPPV. The changes of clinical symptoms, HR, RR, SBP, DBP and arterial blood gas (pH、PaO 2、PaCO 2、SaO 2 ) w ho had no response to conventional theatmen were measured to evaluate the effica cy of NIPPV. Results: After NIPPV, the clinical symptoms of all patients had been improved significantly. Also, the clinical parameters sho wed a statistical differences (P<0.01) compared with those before NIPPV trea tment. Conclusion: NIPPV could improve symptoms and hypoxe mi a in patients with ACPE. Endotracheal intubation could be avoided in the patient s studied. It is a safe and effective method in treating ACPE.