肺经草止咳化痰有效部位的初步筛选

Screening of Effective Ingredients for Relieving Cough and Resolving Phl egm in the Herba Saniculae

目的 :筛选肺经草止咳化痰的有效部位。方法 :通过镇咳实验、祛痰实验、平喘实验和抗炎实验 ,来筛选止咳化痰的有效部位。结果 :肺经草的醋酸乙酯部位和饱和正丁醇部位均有较好的镇咳和祛痰作用 ,其中镇咳作用以饱和正丁醇部位为佳 ,而祛痰作用以醋酸乙酯部位为佳 ;醋酸乙酯部位对急性炎症有一定的作用。结论

Objective: To screen the effective ingredients for relieving cough and resolving phlegm in the herba Saniculae. Method: The effective ingredients are identified by the easing cough experiment, removing phlegm experiment, relieving asthma experiment and anti-inflammation experiment. Result: Both the Ethyl acetate ingredient and the saturated n-Buthyl alcohol ingredient in the herba Saniculae have a good effect on the cough easing action and phlegm removing. Whereas the saturated n-Buthyl alcohol ingredient shows better cough easing action but worse phlegm removing action than the Ethyl acetate ingredient; the Ethyl acetate ingredient also has some effect on the acute inflammation. Conclusion: The effective ingredients for relieving cough and resolving phlegm in the herba Saniculae are total flavones and total saponins.