草鱼对CFRV疫苗免疫应答的研究

THE IMMUNE RESPONSE OF GRASS CARP IMMUNIZED WITH VACCINE CFRV

本文研究了草鱼对CFRV疫苗的免疫应答水平、规律性、免疫效应期及免疫持久性。用该疫苗免疫后的草鱼能产生很强的应答反应,免疫保护力可达80％以上,血清中和抗体效价非常明显地高于对照组。它的免疫效应期在5天以内,第10天血清中和抗体达到较高水平,第20天处于峰值,并可维持20余天,以后在第10天的水平上波动。草鱼对CFRV疫苗的免疫持久性在13个月以上。

The level,regularity,effective phase and continuance of immuneresponse of grass carp immunized with vaccine CFRV were approached in thispaper. Strong response,both more than 80% of percent relative protection (PRP)and significantly higher antiserum neutralization titre(ANT) than control, couldbe produced after immunization. The effective phase of immune response was wi-thin five days and the high level of ANT was reached on the tenthday.On the twenti-eth day, ANT went up to peak level and remained for twenty days then it fluctuated at this level. This research proved that the continuance of immune responseof grass carp immunized with vaccine CFRV was beyond thirteen months.