≤30岁女性乳腺癌患者的临床病理特征和预后

Clinicopathological characteristics and prognosis of breast carcinoma in women aged 30 years or younger

目的 探讨≤ 30岁青年女性乳腺癌患者的临床病理特征与预后的关系。方法 应用回顾性研究及统计学分析的方法 ,研究 1988年 1月 1日～ 2 0 0 2年 12月 31日间 16 9例 30岁及以下女性乳腺癌的临床特点、病理特征及其对预后的影响因素。结果 ≤ 30岁女性乳腺癌总的 3,5 ,10年生存率分别为 6 4 .4 %、5 5 .9%和 5 3.4 % ,平均生存时间为 (110 .39± 9.2 2 )个月。单因素分析显示 ,其预后与患者是否结婚、是否处于妊娠哺乳期以及肿瘤的病理分期、肿瘤大小、淋巴结转移情况有相关性。结论 患者是否结婚、是否处于妊娠哺乳期及肿瘤的病理分期是影响 30岁及以下女性乳腺癌患者术后生存的独立因素。

Objective To explore the relationship between clinicopathologic features and prognosis of breast carcinoma in women aged 30 years or younger.Methods From Jan.1,1988 to Dec.31,2002,the date of clinical characteristics,pathologic features and survival rate of 169 patients with breast carcinoma in women aged 30 years or younger were collected and analyzed retrospectively.Results The overall 3 year-,5 year- and 10 year- survival rates of patients with breast carcinoma were 64.4%,55.9% and 53.4% respectively,with a mean survival time of 110.39±9.22 months.The factors such as marriage,pregnancy/lactation,pathological staging,tumor size and status of lymph nodes influenced the survival rate by univariate analysis.The factors such as marriage,pregnancy/lactation and pathological staging were independent prognostic factors through multivariate analysis.Conclusion Marriage,pregnancy/lactation and pathological staging,as the important independent prognostic factors,can be used to assess the postoperative survival.