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亚铜催化法^(131)I标记间碘苄胍的研究

Study on Method of Cuprous Catalysis for ^(131)I Marking MIBG
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摘要 采用亚铜做催化剂, 研究了131I标记间碘苄胍的方法, 即是沸水浴温度, 标记时间 15 min, 用铜量 2. 5μg和抗坏血酸量5. 0 mg; 纸层析法分析标记物, 标记率大于97%. 此标记方法不需要进一步的分离, 具有简单、快速的特点. A new method for (^(131)I) labeled metaiodobenzyl guanidine (MIBG) was studied using cuprous as catalyst. That is the boiling temperature within 15 minute and 2.5 μg of cuprous, 5.0 mg of ascorbic acid; A labeled efficiency more than 97% is obtained by paper chromatography. The method has characteristic of simple and fast, and it has no need for further separation.
作者 李勇 李红全
出处 《西南师范大学学报(自然科学版)》 CAS CSCD 北大核心 2005年第1期101-103,共3页 Journal of Southwest China Normal University(Natural Science Edition)
关键词 胍乙啶 ^131I-间碘苄胍 亚铜催化 纸层析法 标记 guanethidine (^(131)I)-metaiodobenzyl guanidine cuprous catalysis paper chromatography label
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参考文献5

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