细胞的功能冗余性及其意义

Functional Redundancy of Cells and Its Significance

引入新概念可能推动学科的发展 .近年来冗余性概念已逐步渗入生命科学 ,细胞因子和转录因子的功能冗余性已引起研究者的关注 .但是 ,对细胞冗余性的研究报道尚少 .最近 ,对成体干细胞可塑性和专职吞噬细胞、兼职吞噬细胞的研究进展引发人们对细胞功能冗余性的思索 .综述对细胞冗余性和抗冗余性的有关资料 ,试从生物医学角度探讨细胞冗余性的作用和意义 。

Introduction of new concept may promote science development. In recent years, the concept of redundancy has gradually infiltrated into life science. Functional redundancy of cytokines and transcriptional factors has attracted much attention. However, cellular redundancy remains ill-characterized yet. Recent development in study of adult stem cell plasticity and professional and amateur phagocytes arouse exploration of cellular redundancy. Relevant information concerning cellular redundancy and antiredundancy are summarized, the function and significance of cellular redundancy are discussed from the angle of biomedicine, and active investigation in cellular redundancy is suggested.