细胞传感器与芯片的研究进展

The Progress of Bio-cell Sensor and Cell Chip

细胞传感器(cell basedbiosensor)与芯片(cell basedbiochip)已成为后基因时代生物科学研究的重要工具,它们利用生活细胞作为研究对象或敏感元件,与传感器和芯片技术相结合,通过生物信号与物理、电化学等其他信号的转换,实现实时、快速、微量地检测细胞的功能信息和待测物的性质.在细胞生物学研究、环境监测和药物开发等领域有广泛的应用.综述近三年来细胞传感器与芯片技术的研究进展及应用。

Bio-cell sensor and bio-cell chip techniques have been important tools in post-gene era. They can detect functional information of cells as-well as nature of matters detected. Living cells would be detected as a unit or sensetive element by exchanging between biological signals and physical and electrochemical signals. The detection using these tools is raptive, in real-time, quantitive and qualitive. Bio-cell sensor and bio-cell chip techniques have been applied in fields of the cellular biology, the monitoring of envirement and the developments of drugs. The developments of methods, applications in three years and the trends are reviewed.