110株鲍曼不动杆菌的耐药性分析

Analysis of antibiotic resistant patterns of 110 acinetobacter baumannii isolates

目的 分析鲍曼不动杆菌在临床感染中的耐药特征。 方法 采用美国临床实验室标准化委员会 (NCCLS)推荐的纸片扩散法 ,测定近三年来初次分离的 1 1 0株鲍曼不动杆菌对妥布霉素、头孢拉定和亚胺培南等 1 7种抗菌药物的耐药特征。 结果 鲍曼不动杆菌对妥布霉素、头孢曲松、头孢拉定和亚胺培南的敏感率最高分别为 80 .5 9%、83 .3 3 %、86.67%和 92 .77% ;对氨苄青、头孢唑林、头孢呋辛和氨曲南呈高水平耐药 ,敏感率为 2 .1 5 %～ 7.3 7%。 结论 鲍曼不动杆菌对 1 7种抗菌药物均有不同程度的耐药。

Objective To analyse the antibiotic resistant patterns of acinetobacter baumannii isolates from clinical infections. Methods Susceptible rates of 110 initial isolates against 17 antibiotics were determined by slip diffusion (NCCLS). Results A.baumannii had the higher susceptible rates to tobramycin, ceftiaxome, ceftazidime and imipenem(80 59%,83,33%,86.67%,92.77% respectively);and had the lower susceptible rates to ampicillin, cefazolin, cefuroxine and aztreonam (susceptible rates from 2.15% to 7.37%). Conclusion Against 17 antibiotics, A. baumannii showed different levels of resistance.