期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

艾滋病发病机制中的细胞凋亡理论 被引量：1

Theory of Apoptosis in the Pathogenesis of AIDS
下载PDF
导出
摘要 有关ＨＩＶ感染引起ＣＤ４＋Ｔ淋巴细胞耗竭最终导致艾滋病的确切机制尚不清楚。目前研究最多的仍是细胞凋亡理论，本文就细胞凋亡在艾滋病发病中的作用，凋亡的可能机制两方面进行概述。 The mechanisms whereby HIV causes CD4+T lymphocyte depletion and AIDS occurrence remain poorly understood. Up to now the theory of apoptosis is still the most popular hypothesis. The article reviews the role and probable mechanism of apoptosis in the pathogenesis of AIDS.
作者 池莉 水波 张永容
机构地区 中国医学科学院中国协和医科大学实验动物研究所
出处 《中国实验动物学杂志》 2000年第4期245-249,共5页 Chinese Journal of Laboratory Animal Science
关键词 人免疫缺陷病毒 艾滋病 脱噬作用 HIV(human immunodeficiency virus) AIDS(acquired immunodeficiency syndrome) Apoptosis
分类号 Q255 [生物学—细胞生物学] R512.91 [医药卫生—内科学]
  • 相关文献

参考文献18

  • 1Yamasaki Y, Matsuo Y, Zagorski J, et al. New therapeutic possibility of blocking cytokine-induced neutrophil chemattractant on transient ischemic brain damage in rats [J]. Brain Res, 1997,759 : 103.
  • 2Yurchenco P D, Schittny J C. Molecular architecture of basement membrane [J]. FASEB J, 1990, 1577.
  • 3Rot A. Endathelial cell binding of NAP-1/IL-8 role in neutrophil emigration [J]. Immunol Tody, 1992,13, (8): 291-294.
  • 4Imirovie D, Stan Satoh k. Inflammatory mediators of cerebral enthelium., a role in isehemia brain inflammation [J]. Brain Pathol, 2000, 10 (1): 113-126.
  • 5Matsumoto T, Ikeda K, Mukaida N, et al. Prevention of cerebral edema and infarct incerebral reperfusion injury by an antibody to interleukin-8l[J]. Lab, 1997,77: 119-125.
  • 6Hirano T, Arikira S, Taga T, et al. Biplogocal and clinical aspects of interleukin-6 [J] .Immunol Today, 1990, 11 (12): 443.
  • 7Hirano T. The biology of interleukin-6. Chem Immunol, 1992, 51: 153Uchiyama H, Barut BA,Mohrbacher AF, et al. Adhesion of hunan myelomaderived cell lines to bone marrow stromal cells stimulates interleukin-6 secretion [J] . Blood, 1993,82 (12): 3712.
  • 8Fassbender K, Rossol SKammer T, et al. Proinflammatory cytokines in serum of patients with acute cerebral ischemia: Kinetics of secretion and relation toextent of brain damage and outcome of disease [J].J Neurol Sci, 1992, 36: 1.
  • 9Loddick S A, Yurnbull A V, Rothwell N J. Cerebral interlenkin-6 is neuro protective during permanent focal cerebral ischemia in the rat [J] . Jcereb Blood Flow Metab 1998Feb: 18 (2): 176.
  • 10Feuerstein G Z, Liu T, Barone F C. Cytokone inflammation, and braininjury: role of tumor necrosis factor-alpha. Cerebrovas Brain Metah Rev, 1994, 6 (4) : 341Barone FC, Arvin B, White RF, et al. Tumor necrosis factor-α,Amediatoroffocal ischemic brain injury [J]. Stroke, 1997, 28: 1233.

同被引文献7

  • 1A Perelson, A Neumann, M Markoitz, et al. HIV: Dynamics in Vivo: Virion Clearance Rate, Infected Cell Life-span, and Viral Generation Time [ J ]. Science, 1996,271 : 1582 -1586.
  • 2R V Culshaw, S G Ruan. A Differential Equation Model for HIV Infection of CD4+ T-cells[ J]. Math Biosci,2000(165) :27-39.
  • 3P De Leeheer, H L Smith. Virus Dynamics:A Global Analysis[ J]. SIAM ! Appl Math,2003 (631) :1313-1327.
  • 4Patrick W Nelson, James D Murray, Alan S Perelson. A Model of HIV-I Pathogenesis that Includes an Intracellular Delay [ J ]. Mathematical Biosciences ,2000,163 (2) :201-215.
  • 5L C Wang, M Y Li. Mathematical Analysis of the Global Dynamics of a Model for HIV Infected of CD+4 T-cells [ J ]. Appl Math Comput ,2007 ( 189 ) : 1331-1340.
  • 6A S Perelson,P W Nelson.HIVI Dynamics in Vivo[J].SIAM REV,1999,41:3-44.
  • 7William A O’Brien.艾滋病的治疗与控制[J].中国性病艾滋病防治,2001,7(1):62-63. 被引量：7

引证文献1

中国实验动物学杂志
2000年 第4期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部