启东肝癌患者血清中HBV_2感染标志物的临床分析

A study on HBV_(2) infection of serum of primary liver cancer in Qidong city

目的:了解启东肝癌患者血清中HBV_2感染的情况及与肝癌的关系。方法:对672例肝癌患者血清HBVM检测结果进行分析。结果:(1)672例肝癌血清中HBV_2感染率为4.02％(27/672),占HB_3Ag阳性者的5.29％(27/510);(2)HBV_1与HBV_2混合感染率为1.93％(13/672),占HB_3Ag阳性者的2.55％(13/510)。结论:启东肝癌患者血清中存在HBV_2感染,将来研制乙肝疫苗时应包含有HBV_2之表面抗原。

Purpose: In order to study the relationship between the HBV2 infection and liver cancer. Methods: A study on HBV2 infection on patiants of primary liver cancer was made in Qidong. Sera were obtained from 672 cases of liver cancer. Re-sults: The total infection rate of HBV was 95. 39% (641/672). The infection rate of HBV2 was 4. 02% (27/672), being 5. 29% (27/510) in patients with HB.Ag positive. The mixed infection rate of HBV1 and HBV2 was 1. 93(13/672).Conclusions: Al-though the HBV1 was infected long ago and the anti-HB(?). was produced, the anti-HB(?) was not strong enough to prevent the HBV2 infection again. It suggests that the preparation of vaccines must contain the antigen of HBV2.