螺旋CT扫描结合CA19-9检测在胰腺癌术前分期中的探讨

Dual-Phase Spiral CT Combined with CA19-9: Research on Pancreatic Carcinoma Terminal before Surgery

目的 探讨螺旋CT双期扫描结合CA19 9对判断胰腺癌可切除性方面的价值。方法 回顾性收集 3 7例在我院行螺旋CT双期扫描并经手术病理证实的患者 ,全部患者均有术前血清CA19 9检测结果。结果 CT对胰腺癌不可切除的判断准确率高达 10 0 % ,对可切除性判断准确率只有 78.5 7%。胰腺癌病人中CA19 9的阳性率为 82 .86% ,CA19 9与肿瘤大小有关 ;CA19 9在可切除组与不可切除组间存在显著性差异。结论 螺旋CT结合CA19 9在判定胰腺癌不可切除性方面有一定价值 ,尚不能得出CA19 9对协助CT判定胰腺癌可切除性方面有肯定意义的结论。

Objective To evaluate the value of dual phase helical computed tomography(CT) combined with CA19 9 in correct staging and assessment the resectability in patients suspected to have pancreatic carcinoma. Methods Preoperative CT appearances and serum levels of CA19 9 were retrospectively reviewed in 37 patients. CT results were correlated with surgical and histopathologic results. Serum levels of CA19 9 were measured with commercial radioimmunoassay kits. Results For prediction of unresectability, helical CT had accuracy of 100%; for prediction of resectability, the accuracy was 78.57% . The sensitivity of CA19 9 in detecting pancreatic carcinoma was 82.86%; CA19 9 level has correlation with the size of cancer; the serum levels of CA19 9 of unresectable patients was significantly higher than resectable patients. Conclusion For prediction of unresectability, helical CT has an higher accuracy, but to predict resectability, the accuracy is poor. Now we can't conclude that dual phase spiral CT combined with CA19 9 are well than dual phase spiral CT in evaluating the pancreatic carcinoma. [