冠心病患者经皮冠状动脉腔内成形术前后QT离散度改变

QT dispersion in patients with coronary artery disease underwent PTCA

目的:12导联心电图 QT 离散度增大在冠心病患者是预测室性心律失常事件的有用指标。旨在估价冠心病患者行经皮冠状动脉腔内成形术(PTCA)前后对 QTd 的影响。方法:对21例冠心病患者行 PTCA 术后 QTd 进行分析。男性17例,女性4例。平均年龄56.5岁,患者为单支血管病变。本组对 PTCA 术前后12导联心电图 QTd 及 QTcd 进行测定。结果:术后与术前比较 QTd 及 QTcd 均有明显减少(P<0.01)。结论:冠心病患者 QFd 及 QTcd 明显增大,并在 PTCA 术后随着缺血及心室复极不一致的改善而降低。

Objective:Increased QT dispersion in 12 lead ECG has been suggested as a potential tool for prediction of arrhythmic events in patients with coronary artery disease.The purpose of this study was to evaluate the effect of angioplasty(PTCA)on QTd.Methods:QTd in 21 patients(male 17,famale 4, mean age of 56.5 years)with coronary artery disease underwent PTCA were analysed.They were diag- nosed as single vessle disease and were selected for PTCA.QTd(QTmax-QTmin)and QTcd(corrected QTd)were obtained by measurement of standard 12 lead ECGs before and after PTCA.Results:QTd and QTcd after PTCA revealed significant reduction compared with those before PTCA.Conclusion: QT dispersion was significantly decreased after PTCA due to improvement of ischemia and heterogeneous repolarization in patients with coronary artery disease.