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基因导向性个体化用药新模式 被引量：11

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摘要 随着新世纪的到来和生命科学的迅猛发展,人类对药物治疗的要求发生了重大变化.
作者 周宏灏
机构地区 中南大学临床药理研究所
出处 《中南药学》 CAS 2003年第1期5-10,共6页 Central South Pharmacy
关键词 个体化用药 基因 诊断 药物治疗 对药 导向治疗 使药 新模式 发展 实行
分类号 R969 [医药卫生—药理学] R289.1 [医药卫生—方剂学]
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参考文献16

  • 1[1]Gonzalez FJ,Skoda RC,Kimura S, et al.Characterization of the common genetic defect in humans deficie nt in debrisoquine metabolism.[J]Nature,1988,331(6155):442.
  • 2[2]Xiao ZS,Goldstein JA,Xie HG,et al.Diffeences in the incidence of the CYP2C19 polymorphism affectiong th e S-mephenytoin phenotype in Chinese Han and Bai populations and identification of a new rare CYP2C19 mutant allile[J].J Pharmacol Exp Ther,19 97,281:604.
  • 3[3]Wan J,Xia HeN,He N,et al. The elimination of diazepam in Chinese subjects is dependent on the mephenytoin oxida tion phenotype[J].Br J Clin Pharmacol,1996,42:471.
  • 4[4]Qin XP,Xie HG,Wang W,et al.Effect of the gene dosage of CYP2C19 On diazepam metabolism in Chinese subjec ts[J].Clin Pharmacol Ther.1999,66:842.
  • 5[5]Martinez FD,Graves PE,Baldini M, et al .Association between Genetic Polymorphisms of the 2-Adrenoceptorand Resp onse to Albuterol in Children with and without a History of Wheezing.J[J].Clin.Invest.1997,100:3184.
  • 6[6]Haas M,Yilmaz N,Schmidt A,et al .Angiotensin-converting enzyme gene polymorphism determines the antipro teinuric and systemic hemodynamic effect of enalapril in patients with proteinur ic renal disease.Austrian Study Group of the Effects of Enalapril Treatment in P roteinuric Renal Disease[J].Kidney Blood Press Res, 1998,21( 1):66.
  • 7[7]Benetos A,Cambien,F,Gautier,S, e t al.Influence of the angiotensin II type 1 receptor gene polymorphism o n the effects of perindopril and nitrendipine on arterial stiffness in hypertens ive individuals[J].Hypertension,1996,28:(6) 1081.
  • 8[8]van Essen GG,Rensma PL,de Zeeuw D,et al.Association between angiotensin-converting-enzyme gene polymor phism and failure of renoprotective therapy[J].Lancet,1996,3 47(8994):94.
  • 9[9]Arranz M,Collier D,Soclhi M,et a l.Association between clozapine response and allelic variation in 5-HT2A recepter gene[J].Lancet,1995,29(346):281.
  • 10[10]Poirier J,Delisle M,Quirion R,e t al.Apolipoprotein E4 Allele as a Predictor of Cholinergic Deficits and Treatment Outcome in Alzheimer Disease[J].Proceedings of the National Academy of Sciences[J],92,12260,1995.National Academy of Sci ences.

同被引文献135

引证文献11

二级引证文献85

中南药学
2003年 第1期

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