摘要
选用氯化铝溶液制备拟痴呆大鼠动物模型,研究智力王胶囊对拟痴呆大鼠脑记忆功能及大脑皮层组织(Cer)中胆碱酯酶(AchE)活性的影响。结果表明:智力王胶囊可使痴呆大鼠脑的记忆功能改善(P<0.01),Cer中AchE活性比正常青年大鼠明显提高(P<0.01)。提示智力王胶囊有防治脑功能减退和防治早老性痴呆的作用。
Dementia mimetic rat model was formed with aluminum chloride solution in order to study the effect of zhiliwang (ZLW) capsule on the memory and the Acetylcholinesterase (AchE) activity in the model's cerebral cortex(Cer). Results showed that the ZLW could improve the model's cerebral memory and the AchE in-creased in the model evidently as compared with the healthy young rats. These results suggested that ZLW is effective in preventing the degeneration of cerebal funtion and presenile dementia.
出处
《安徽医药》
CAS
1997年第1期10-12,共3页
Anhui Medical and Pharmaceutical Journal
基金
国家中医药管理局青年科研基金