MRI MnDPDP增强对原发性肝细胞癌的诊断价值

Diagnostic Value of MnDPDP Enhanced MRI in Primary Hepatocellular Carcinoma

目的 :评估MRIMnDPDP增强不同延迟时间成像对原发性肝细胞癌的诊断价值。材料和方法 :对 3 6例HCCs行MRIMnDPDP增强研究。静脉滴注MnDPDP结束后 5min开始每隔 5min成像 1次 ,直至 40min ;第二天行延迟 2 4h成像。成像序列为SET1WI和FMPSPGRT1WI。对不同延迟时间图像的信噪比 (S/N)、对比度噪声比 (C/N)及病灶显示率进行比较研究。结果 :(1)不同延迟时间图像的S/N无统计学差异。 (2 ) 5～ 2 5min图像肝与HCC之间C/N高于 3 0min以后图像 (P<0 0 5 )。 (3 )病灶显示率和定性率均以延迟 2 4h最高 (92 7% ) ,但各组图像之间无显著差异。结论 :MnDPDP增强MRI的HCC显示率和定性率均以延迟 2

Purpose: To evaluate the diagnostic value of MnDPDP enhanced MRI at different delayed times for primary hepatocellular carcinoma (HCC). Materials and Medthods: Thirty six patients of HCCs were investigated with MnDPDP enhanced MRI. The images were performed at every five minutes until 40 minutes after the end of intravenous infusion of MnDPDP, and the 24 hour delayed images were obtained the next day. The imaging sequences were T 1WI SE and T 1WI FMPSPGR. The S/N, C/N and the lesion detectability were compared for the images on the basis of delayed times. Results: (1) The S/N±S was not equal to each other according to the delayed times, but there was no statistical significance existed among them; (2)The C/N±S of the postcontrast images at 5～25 min were higher than that at and after 30 min (P<0 05); (3) The highest detection rate and charactersisation of HCCs were reached at 24 hour delayed images. Conclusion: The 24 hour delayed image of MRI enhanced with MnDPDP were the best one for detection and characterisation of HCCs.