蛛网膜下腔出血急性炎症反应综合征与预后的关系

Analysis of the relation of acute inflammatory response syndrome and prognosis in subarachnoid hemorrhage

目的 探讨蛛网膜下腔出血 (SAH)急性炎症反应综合征 (AIRS)与预后的关系。方法 15 4例 SAH患者 ,以下标准≥ 2项者诊断为 AIRS:T<36℃或 >38℃ ,心率 >90次 /分钟 ,呼吸 >2 0次 /分钟 ,血 WBC<4 0 0 0 /mm3或 >12 0 0 0 / mm3。根据 Glasgow评分对 AIRS标准和其它预后因素进行评估。结果 AIRS与 Hunt- Hess和Hess临床分级评分差、CT表现出血量大和血糖增高明显相关。 AIRS患者病死率高于非 AIRS患者。在 AIRS标准中 ,心率、呼吸、WBC是影响预后的独立因素。结论 伴有 AIRS的 SAH患者脑组织广泛损害、临床症状重、预后差。

Objective To explore the relation of acute inflammatory response syndrome (AIRS) and prognosis after subarachnoid hemorrhage(SAH)Methods In 154 patients with SAH,the criteria of AIRS was assessed according to the presence of ≥2 of the following:temperature of <36℃ or>38℃,heart rate of >90 times/min,respiratory rate>20times/min,white blood cell(WBC)of <4000/ mm3or>12000/ mm3,and AIRS criteria and other prognostic were evaluated as predictors of Glasgow Outcome Scale scoreResults AIRS was highly related to poor Hunt-Hess clinical grade,a large amount of SAH on CT,and high plasma glucose concentrationThe occurrence of AIRS was associated with higher mortality rates than that of the nonoccurrenceAmong AIRS criterias,hert rate,respiration rate,and WBC were significant affect predictorsConclusion SAH with AIRS patients were extent damage of brain,producing clinical woesening and a poor outcome