脑梗死病人血浆D-二聚体水平的变化及其在预后判断中的意义

The Fluctuation of Plasma D-Dimer Level in Patients with Cerebral Infarction and its Significance in Prognosis Judgement

目的 探讨脑梗死病人急性期和恢复期血浆D -二聚体水平的变化及其在诊断和预后判断中的意义。方法 采用散射比浊法检测 65例脑梗死病人急性期和恢复期以及 3 0例健康体检者的血浆D -二聚体水平 ,脑梗死组急性期的血浆D -二聚体水平与对照组进行比较 ,并根据恢复期血浆D -二聚体水平比急性期下降或上升把病人分为两组 ,分别对其预后进行观察和比较。结果 脑梗死组急性期血浆D -二聚体水平与正常对照组相比有统计学意义 (P <0 .0 1) ;恢复期血浆D -二聚体水平比急性期下降病人预后良好 ,D -二聚体水平上升者预后不良(P <0 .0 1)。结论 脑梗死病人急性期和恢复期血浆D

Objective To explore the fluctuation of plasma D-dimer level of acute phase and convalescence phase and its significance in the prognosis judgement in Cerebral Infarction.Methods Test the plasma D-dimer of patients with cerebral infarction(n=65) in acute phase and convalescence phase as well as normal humans(n=30) with scatter nephelomete method.Make a comparison of the plasma D-dimer level between the acute phase and the normal control group,and according to the plasma D-dimer level in convalescence phase descends or ascends than those in acute phase, the patients were separated into two groups,observe and compared the prognosis of two groups.Results The patients in acute phase compared with normal control group, D-dimer level was very significantly different(P<0.01), The group whose plasma D-dimer descends in convalescence phase were better in prognosis than the ascending one(P<0.01).Conclusion The fluctuation of plasma D-dimer level in patients with cerebral infarction has, to some extent, instructive significance to the prognosis judgement.