C反应蛋白检测在冠心病中的应用价值

Applyment value of delermining C-reactive protein in coronary artery disease

目的探讨C反应蛋白(CRP)水平测定在冠心病的应用价值。方法冠心病组(96例)分为3组,稳定型心绞痛(SAP)组26例,不稳定型心绞痛(UAP)组30例,急性心肌梗死(AMI)组40例。比较冠心病组各组间及与对照组(30例)之间CRP、白细胞(WBC)水平差异。结果SAP组与正常对照组相比,CRP水平有所升高,但无统计学意义(P>0.05);UAP组、AMI组CRP水平显著高于SAP组和对照组(P<0.01);冠心病各组WBC水平均高于正常对照组(P<0.01),但SAP组和UAP组WBC无显著差异(P>0.05),并且未高于正常上限。结论CRP是冠心病的独立危险因素。CRP升高提示冠心病的严重程度。

Objective To investigate the applyment value of delermining C-reactive protein(CRP) in coronary artery disease(CAD). Methods The patients with CAD (CAD group, 96 cases) were divided into three subgroups, 26 cases of stable angina pectoris (SAP) group, 30 cases of unstable angina pectoris (UAP) group, 40 cases of acute mycocardial infarction (AMI) group. Compaired the level of CRP, white blood cell(WBC) in three subgroups with that in controls (30 cases). Results The level of CRP in SAP group were higher than those in control group, with no statistics significance (P>0.05), the level of CRP in UAP and AMI groups were remarkable higher than SAP groups and those in control group(P<0.01); the level of WBC in all CAD groups were higher than those in control group, but the level of WBC had no remarkable differences between SAP group and UAP group, neither haigher than normal upper limit. Conclusions The level of CRP is an independent risk factor for CAD. Elevated CRP can reflect the order of severity of CAD.