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P-选择素与冠状动脉疾病关系的研究进展

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摘要 本文综述了 P-选择素与冠状动脉粥样硬化疾病关系近几年的研究进展。包括:P-选择素与冠状动脉粥样斑块的形成,与冠状动脉粥样斑块的不稳定性以及与血栓的形成;P-选择素与冠状动脉疾病临床表现;抗 P-选择素的治疗。
作者 屈晓冰 孙振球 谢景超
机构地区 中南大学湘雅二医院老年病科 中南大学公共卫生学院
出处 《国外医学（老年医学分册）》 2005年第1期15-20,共6页 Foreign Medical Sciences(Geriatrics)
基金 湖南省自然科学基金(04JJ3106)
关键词 P-选择素 冠状动脉疾病 粥样斑块 治疗 研究进展 冠状动脉粥样硬化 血栓 形成 不稳定性
分类号 R543 [医药卫生—心血管疾病]
  • 相关文献

参考文献32

  • 1陈宇杰,陆信武,蒋米尔.P-选择素与动脉粥样硬化形成[J].国外医学（生理病理科学与临床分册）,2002,22(4):323-325. 被引量：7
  • 2马晶茹,胡健.P-选择素与心血管病的研究进展[J].沈阳医学院学报,2003,5(1):55-56. 被引量：4
  • 3Shebuski RJ, Kilgore KS. Role of inflammatory mediators in thrombogenesis. J Pharmacol Exp Ther, 2002; 300(3): 729-735.
  • 4Evangelism V, Manarini S, Sideri R et al. Platelet/polymorphonuclear leukocyte interaction: P - selectin triggers protein- tyrosine phosphorylation- dependent CD11b/CD18 adhesion: Role of PSGL- 1 as a signaling molecule.Blood, 1999; 93 (3): 876-885.
  • 5Frenette PS, Denis CV, Weiss L,et al. P - selectin glycoprotein ligand 1 (PSGL-1) is expressed cn platelets and can mediate platelet - endothelial interactions in vivo. J Exp Med, 2000; 191:1413-1422.
  • 6Carter AM, Anagnostopoulou K, Mansfield MW et al.Soluble P- selectin levels, P - selectin polymorphisms and cardiovascular disease. J Thromb Hamaost, 2003; 1 (8) :1718- 1723.
  • 7Barbaux SC, BlankenbergS, Rupprecht HJ et al. Association between P- selectin gene polymorphisms and soluble P-selectin levels and their relation to coronary artery disease. Arterioscler Thromb Vasc Biol, 2001; 21 (10):1668- 1673.
  • 8Blake GJ, Ridker PM. Novel clinical markers of vascular wall inflammation. Circ Res, 2001; 89 (9): 763-771.
  • 9Dong ZM, Brown AA, Wagner DD. Prominent role of P-selectin in the development of advance atherosclerosis in apoE- deficient mice. Circulation, 2000; 101:2290-2295.
  • 10Phillips JW, Barringhaus KG, Sanders JM et al. Single injection of P - selectin or P- selectin glycoprotein ligand -1 monoclonal antibody blocks neointima formation after arterial injury in apolipoprotein E- deficient mice. Circulation, 2003; 107 (17): 2244-2249.

二级参考文献24

  • 1金佰泉.细胞和分子免疫学[M].西安：世界图书出版公司,1995.42-43.
  • 2Shimomura H, Ogawa H, Arai H, et al. Serial changes in plasma levels of soluble P-selectin in patients with acute myocardial infarction[J]. Am J Cardiol, 1998, 81(4): 397-400.
  • 3Ridker PM, Buring JE, Rifai N. Soluble P-selectin and the risk of future cardiovascular events[J]. Circulation, 2001, 103(4): 491 - 495.
  • 4Murohara T, Parkinson SJ, Waldman SA, et al. Inhibition of nitric oxide biosynthesis promotes P-selectin expression in platelets. Role of protein kinase C[J]. Arterioscler Thromb Vasc Biol, 1995, 15(1): 2068-2075.
  • 5Murohara T, Scalia R, Lefer AM. Lysophosphatidylcholine promotes Pselectin expression in platelets and endothelial cells. Possible involvement of protein kinase C activation and its inhibition by nitric oxide donors[J] . Circ Res, 1996, 78(5): 780 - 789.
  • 6Khew-Goodall Y, Wadham C, Stein BN, et al. Stat6 activation is essential for interleukin-4 induction of P-selectin transcription in human umbilical vein endothelial cells [J]. Arterioscler Thromb Vasc Biol,1999, 19(6): 1421-1429.
  • 7Nomura S, Shouzu A, Omoto S, et al. Effect of cilostazol on soluble adhesion molecules and platelet-derived microparticles in patients with diabetes[J] .Thromb Haemost, 1998, 80(3):388 - 392.
  • 8Lee CS, Choi JM, Pak DH, et al. Inhibition of expression of P-selectin by antioxidant in cholesterol-fed rats[J]. J Korean Med Sci, 1999, 14(1):8-14.
  • 9Li LX, Chen JX, Liao DF, et al. Probucol inhibits oxidized-low density lipoprotein-induced adhesion of monccytes to endothelial cells by reducing P-selectin synthesis in vitro[J]. Endothelium, 1998, 6(1): 1-8.
  • 10Xie X, Rivier AS, Zakrzewicz A, et al. Inhibition of selectin-mediated cell adhesion and prevention of acute inflammation by nonanticoagulant sulfated saccharides. Studies with carboxyl-reduced and sulfated heparin and with trestatin a sulfate[J]. Biol Chem, 2000, 275(44): 34818-34825.

共引文献9

国外医学（老年医学分册）
2005年 第1期

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