肿瘤的自杀基因治疗研究进展

Sucide gene therapy and research progress in carcinoma

肿瘤的自杀基因治疗法是一种具有潜在临床应用价值的新的肿瘤治疗策略。综述了近年来自杀基因疗法在肿瘤治疗中取得的研究进展 ,分别从自杀基因作用机制、自杀基因体系、载体的构建、旁观者效应、自杀基因与免疫反应、联合基因治疗等几个方面进行综述。

Sucide gene therapy of carcinoma is a promising strategy in the clinic. We reviewes the advances of mechanism, system, vector construction, bystander effect and combining gene therapy on sucide gene therapy of carcinoma.