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肾细胞癌转移的分子机制及相关遗传学特征 被引量:3

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摘要 肾细胞癌 (RenalCellCarcinoma ,RCC)是泌尿系统常见恶性肿瘤 ,生物学行为复杂 ,个体差异大。RCC转移具有明显的不确定性 ,是RCC致死的主要原因 ,预后极差。RCC微环境血供丰富 ,淋巴网络发达 ,为RCC的生长和转移提供有利条件 ;RCC转移由其特定的基因组遗传和表观遗传与器官微环境之间相互作用决定的。本文就RCC转移的基础知识、基因组遗传、表观遗传等方面进行综述 ,为研究RCC的转移机制 。
出处 《国外医学(泌尿系统分册)》 2005年第1期8-12,共5页 Foreign Medical Sciences(Urology and Nephrology Foreign Medical Sciences)
关键词 肾细胞
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