医院内感染非发酵革兰阴性杆菌的病原学与耐药性监测研究

Pathogenic and antimicrobial resistance study on nonfermenters gram negative bacilli causing nosocomial infection

Objective To investigate the isolation and antimicrobial resistance of nonfermenters gram negative bacilli(NFGNB) causing nosocomial infection Methods Data about NFGNB reported to the national nosocomial infection surveillance system in recent three years were analyzed Results NFGNB accounting for 19 68% of the pathogens reported at the same period, and accounting for 42 41% of gram negative bacilli The constitutional rate of P aeruginosa, A baumannii and S maltophilia was 46 53%, 19 88% and 7 35% respectively During the period of three years, the constitutional rate of A baumanniirose from 13 27% to 23 50%, the constitutional rate of S maltophilia rose from 5 93% to 8 44% There were significant difference in antimicrobial resistance among different NFGNB P aeruginosa had low resistance to imipenem, ceftazidime, cefoperazone Acinetobacter had low resistance to imipenem, ciprofloxacin;S maltophilia had low resistance to SMZ, ciprofloxacin, cefoperazone Conclusion NFGNB was an important pathogen causing nosocomial infection, especially P aeruginosa, A baumannii and S maltophilia It is important to strengthen the surveillance of nosocomial infection caused by NFGNB and antimicrobial

Objective To investigate the isolation and antimicrobial resistance of nonfermenters gram negative bacilli(NFGNB) causing nosocomial infection Methods Data about NFGNB reported to the national nosocomial infection surveillance system in recent three years were analyzed Results NFGNB accounting for 19 68% of the pathogens reported at the same period, and accounting for 42 41% of gram negative bacilli The constitutional rate of P aeruginosa, A baumannii and S maltophilia was 46 53%, 19 88% and 7 35% respectively During the period of three years, the constitutional rate of A baumanniirose from 13 27% to 23 50%, the constitutional rate of S maltophilia rose from 5 93% to 8 44% There were significant difference in antimicrobial resistance among different NFGNB P aeruginosa had low resistance to imipenem, ceftazidime, cefoperazone Acinetobacter had low resistance to imipenem, ciprofloxacin;S maltophilia had low resistance to SMZ, ciprofloxacin, cefoperazone Conclusion NFGNB was an important pathogen causing nosocomial infection, especially P aeruginosa, A baumannii and S maltophilia It is important to strengthen the surveillance of nosocomial infection caused by NFGNB and antimicrobial resistance