脑脊液生化异常与结核性脑膜炎患者病情的关系

Relationship Between Biochemical Changes of Cerebrospinal Fluid and the Clinical Features of Tuberculous Meningits

目的 :探讨脑脊液生化改变对于结核性脑膜炎 (结脑 )的诊断、病情和预后评估的价值。方法 :回顾性分析 86例结脑患者的脑脊液生化改变与其临床特点的关系。结果 :结脑患者的脑脊液糖降低率为 73 3 % ,氯化物降低率为 72 1% ,蛋白质升高率为89 5 % ;脑脊液生化异常项目越多 ,其临床症状越严重 ,但与预后无明显相关性。结论 :脑脊液生化改变对于结脑的诊断、病情评估仍有一定价值。

Aim:To investigate values of biochemical analysis of cerebrospinal fluid(CSF) on the diagnosis and prognosis of tuberculous meningitis(TM).Methods:86 cases of TM were analysed retrospectively.Results:A decreased level of glucose,chloride and increased level of protein was found 73.3%,72.1%,89.5% respectively in the patients with TM.The more there were items of biochemical changes,the more patients had a severe disease,but they were no value on the prognosis.Conclusion:Biochemical analysis of CSF is helpful in the diagnosis and prognosis of TM.