颌骨牙骨质化纤维瘤临床与病理研究

A Clinical-Pathologic Study of Cementifying Fibroma of Jaws

目的 观察颌骨牙骨质化纤维瘤 (CF)的临床病理特征。方法 收集CF 4 3例 ,对其临床表现、X线影像及病理特征等进行回顾性分析研究。结果 临床表现为颌骨局部肿物 ,以 10～ 19岁、30～ 4 9岁年龄组女性好发 ,下颌骨多见。X线呈界限清楚的单囊或多囊透射区 ,其内有密度增高的斑点状影。镜下见纤维结缔组织中有散在的牙骨质小体 ,其中 9例同时伴有化骨趋向 (牙骨质 -骨化纤维瘤 ,COF)。结论 该瘤易与其他病变混淆 ,病理检查是确诊依据 ,CF(COF)

Objective To study the clinical characteristics of pathology and diagnosis of cementifying fibroma(CF) of the jaws. Methods The data including clinical characteristics,X-rays, and histologic features of 43 cases were reviewed and analysed retrospectively. Results Clinical features seemed to have particular prediction for mandible,mainly in females aged 10-19 years old and 30-49 years old. Radiographically,the lesions appeared as cystic radiolucencies with clear border and variable amounts of radiopaque materials. Cementicles could be seen in pathological changes and 9 cases showed cemento-ossifying fibroma(COF). Conclusions The differential diagnosis is important as CF is always confused with other lesions of the jaws. Making a definite diagnosis depends on pathological changes. CF(COF) and ossifying fibroma belong to the same kind of lesions through the analyses.