1Tseng JF,Mulligan RV.Gene therapy for pancreatic cancer[J].Surg Oncol Clin N Am,2002,11:537-569.
2Rigg AS,Lemoine NR.Genetic prodrug activation therapy for pancreatic cancer[J].Ann N YAcad-Sic,1999,880:319-325.
3Liang Z,Liu T.Progress of gene therapy in pancreatic carcinoma[J].Zhonghua Bing Li Xue Za Zhi.2002,31:548-550.
4Haack K,Linnebacher M,Eisold S,et al.Induction of protective immunity against syngeneic rat cancer cell by expression of the cytosine deaase suicide gene[J].Cancer Gene Ther,2000,7:1357-1364.
5Ohashi M,Kanai F,Tanaka T et al. In vivo adenovirus-mediated prodrug gene therapy for carcinoembryonic antigen-producing pancreatic cancer[J].Jpn J Cancer Res,1998,89:457-62.
6Makinen K, Loimas S,Wahlfors J,et al.Evaluation of herpes Simplex thymidine Kinase mediated gene therapy in experimental pancreatic cancer[J].J Gene Med,2002,2:361-367.
7Pan X,Li ZS,Xu GM Adenovirus-mediated gene transfer in the treatment of pancreatic cancer[J].Pancreas,2003,26(3):274-278.
8Kasuya H,Nomoto S,Nakao S, et ak.The potential of gene therapy in the treatment of pancreatic cancer[J].Drugs Today (Barc),2003,38:457-464.
9Trinh QT,Austin EA,Murray DM,et al.Enzyme/prodrug gene therapy:comparision of Cytosin deaminas fluocrocy-tosineVersusthymidine,Kinase/gancicloviv,enzyme-prodrug systems in a human colorectal Carcinoma cell line[J].Cancer Res,1995,55:4808-4812.
10Yang L,Chiang Y,Len HJ,et al.Intercellular.communication mediates the bystander effect during Herpes simplex thymidine Kinase/ganciclovir-based gene therapy of human gastrointestinal tumor cells[J].Hum Gene Ther,1998,9:719-728.
