生存素在神经系统疾病中的研究进展

Role of survivin in neurologic diseases

生存素是新近发现的一种结构独特的凋亡抑制蛋白,由于它能抑制各种因子诱导的细胞凋亡、参与血管的形成,因此在缺血性卒中、多发性硬化、阿尔茨海默病的病理生理过程中可能发挥了重要作用,并在这些疾病的临床治疗中具有较大的应用价值。

Survivin, as a unique structural inhabitor of apoptosis protein, can inhabit cellular apoptosis induced by various factors, participate the forming of vascular and play an important role in the pathophysiological process of ischemic cerebrovascular disease, multiple sclerosis and Alzheimer's disease. Therefore, survivin has a considerable value in clinic application.