重症监护病房医院真菌感染危险因素分析

Risk factors of Iatrogenic Fungal Infection in Intensive Care Unit

目的分析我院重症监护病房(ICU)患者深部真菌感染的危险因素,并探讨其控制对策。方法采用回顾性调查方法,对我院ICU科2003年1月～2004年2月收治的530例患者逐一调查。结果ICU患者深部真菌感染的发生率为23.96%;感染部位以下呼吸道最多,其次为腹腔、尿道、血液及胆道等;且近年有明显上升趋势;基础疾病以急性脑血管病变、重症胰腺炎患者及介入性诊疗患者感染例次率最高。结论应加强对ICU高龄、脑外伤、重症胰腺炎等医院真菌感染高危疾病的监控,以减少患者并发症、控制医疗成本。

OBJECTIVE To analyze the risk factors of deep fungal infection in ICU-cared patients of our hospital, and discuss the strategy of this disease control. METHODS A total of 530 patients who were admitted to our ICU ward from Jan 2003 to Feb 2004 were investigated with retrospective method. RESULTS The percentage of deep fungal infection in ICU-cared patients of our hospital was 23.96%, the most common infection site was lower respiratory tract, the other common positions were abdomen cavity, urethra, blood and bile duct, etc. The prevalence of deep fungal infection in our ICU patients had a significantly increasing tendency, the basic diseases are usually acute brain vascular disease, heavy pancreatitis and patients which have received intervention diagnosis and treatment. CONCLUSIONS We should intensify the inspection of the patients, which have elder age, brain trauma, heavy pancreatitis, etc. in ICU ward, so that the complication and medical cost of patients can be effectively controlled.