焦虑情绪对老年高血压病患者左室肥厚的影响

Effect of anxiety on ventricular hypertrophy in old patients with primary hypertension

目的探讨焦虑情绪对老年高血压病患者降压疗效及左室肥厚的影响.方法老年高血压病患者根据汉密顿焦虑量表(HAMA)测定,阳性分成2组(A、B组),A组38人;B组34人;阴性为C组35人.三组均口服氨氯地平降压治疗,每次5mg,每日1次,A组病例同时加用抗焦虑治疗,黛力新片10.5mg,每日1～2次.疗程均为6个月.结果 A、B、C三组降压有效率分别为89.47%、67.65%、82.86%,有显著差异.C组降压治疗后左心室重量指数(LVMI)显著下降,与B组相比LVMI的下降有显著差异,加用抗焦虑治疗后A组LVMI亦显著下降,与B组比较有显著差异.结论在伴有焦虑情绪的老年高血压病患者中,焦虑障碍可明显降低降压疗效,而抗焦虑治疗可以明显提高疗效,并且有助于改善伴有焦虑情绪的老年高血压病患者左室肥厚.

Objective To study the effects of anxiety on blood pressure and ventricular hypertrophy in old patients with primary hypertension.Methods Hypertensive patients were divided into three groups. The group A and B were those who got positive result during HAMA scale rating and those who got normal scores belong to group C. All the patients were treated with oral dose of Amlodipine for six months, while the group A patients took Deanxit once every day. Results The effective rates of decrease blood pressure in three groups were 89.47%、67.65%、82.86%, respectively. Compared with group B, there was a significant higher effective rate of decreasing blood pressure in group A with anti-anxiety therapy, similar inclusion on improvement of ventricular hypertrophy.Conclusion Anxious emotion may decrease the curative effect of anti-hypertension drug. Anti-anxiety therapy is helpful to treatment of hypertension and improvement of ventricular hypertrophy in old hypertensive patients with anxiety.