放射性核素显像早期诊断帕金森病的研究进展

Research progress of the radioactive isotope imaging in diagnosis of early Parkinson’s disease

帕金森病(PD)是中老年人的常见病之一,严重危害中老年人的生活质量。目前尚无有效的治愈方法,但 早期诊断对于提高疗效有重要意义。核医学领域利用单光子发射电子计算机断层扫描(SPECT)和阳电子发射断 层摄影术(PET)有了很大进展,有望发展成为一种或几种临床常规诊断方法,而这应归功于性能优良的显影剂的 研制成功。本文对此进行综述。

Parkinson disease(PD) is a common disease in the middle-aged and elderly population,which may affect their quality of life.Nowthere are no effective curing methods,however,the early diagnosis is important for heightening the therapeutic effect.In nuclear medicine,people have achieved great progress in utilizing SPECT and PET, which will become one or several common diagnosis means. This owes to the successful development of the imaging agent with superior behavior.