青黄膏的质量标准研究

Study on quality standard of Qinghuang Plaster

目的 建立青黄膏的质量标准。方法 采用薄层色谱法对制剂中的赤芍、夏枯草、连翘进行鉴别,采用高效液相色谱法测定制剂中大黄素的含量。结果 在薄层色谱中以赤芍、夏枯草、连翘对照药材为对照能较好地鉴别出制剂中的赤芍、夏枯草、连翘,高效液相色谱法能准确地测定出制剂中大黄素的含量,大黄素进样量在 0 0 8～ 0 4 0 μg之间呈良好的线性关系,r =0 9993,平均加样回收率为 99 6 3%,RSD为 1 4 1%。结论 此方法简单可行,能快速准确地对青黄膏进行鉴别和含量测定。

Objective To establish the quality standard of Qinghuang Plaster.Methods Radix Paeoniae Rubra,Spica Prunellae,Fructus Forsythiae were identified by TLC,and the content of Emodin was determined by HPLC.Results Radix Paeoniae Rubra,Spica Prunellae,Fructus Forsythiae could be identified by TLC.Emodin showed a good linear relationship at range of 0.08～0.40μg,r=0.9993.The average recovery was 99.63%,and RSD was 1.41%.Conlusion The method is accurate and can be used to control the quality of Qinghuang Plaster.