肝病住院患者抗菌药物使用调查

Antimicrobial agents usage in inpatients of hepatic disease:survey and analysis

目的了解肝病住院患者抗菌药物的使用情况。方法对62例肝病住院患者抗菌药物的应用进行调查。结果抗菌药物的使用率为2581%;单用占7500%;主要抗菌药物为哌拉西林、阿莫西林和头孢曲松;用药途径以静脉以及口服+静脉为主;以治疗性用药为主,预防用药在住院患者中的总使用率为484%;细菌标本送检率仅为625%。结论减少预防性用药,严格掌握抗菌药物的使用可降低抗菌药物的应用率;对于复数耐药菌感染应采取联合用药;提高细菌标本的送检率对于抗菌药物的合理应用十分重要;加强临床医师的抗菌药物知识更新和公众普及教育。

Objective To investigate antimicrobial agents used in inpatients of hepatic diseases. Method Prevalence survey was made to analyze the usage rate of antimicrobial agent in 62 inpatients of liver diseases of a teaching hospital.Results Percent of antimicrobial agent using was 25.81%;Single application rate was 75.00% mainly through intravenous route;The most frequently used antimicrobial agents were Piperacillin,Amoxillin,Ceftriaxion;Antimicrobial agents were mainly used for treatment,preventive usage rate in all the inpatients surveyed was 4.84%;The bacterial examination rate was only 6.25%.Conclusions Decreasing of preventive usage,keeping a tight antimicrobial regime could reduce the usage rate of antimicrobial agent;A combination usage was recommended for multi-resistantant multi-strains infections;Increasing bacterial examination rate was important for appropriate using of antimicrobial agents.It was necessary that medical professionals be informed with newly antimicrobial messages as well as public education.