江苏省肠道线虫病不同流行区集体化疗远期效果监测

Surveillance on long-term efficacy of mass chemotherapy against intestinal nematodiasis in different endemic areas of Jiangsu Province

目的观察肠道线虫病不同流行区集体化疗的远期效果,分析影响因素,为防治工作提供决策依据。方法在通过集体化疗达到控制肠道线虫病流行的3个村,监测停止化疗3年和5年后人群肠道线虫感染和土壤中虫卵、钩虫幼虫污染情况,并对流行因素进行分析。结果经济文化卫生条件较好的苏南、苏中试点村人群肠道线虫感染率继续下降,经济卫生条件和居民卫生行为较差的苏北试点村人群肠道线虫总感染率和各虫种感染率显著回升。土壤中虫卵污染情况和人群感染率的变化相一致。结论肠道线虫病不同流行区集体化疗的远期效果差异有显著性,经济文化卫生条件和个人行为对巩固控制成果具有重要作用。

Objective To observe the long-term efficacy of mass chemotherapy against intestinal nematodiasis in different endemic areas and evaluate the influence factors so as to provide scientific basis for decision making of control strategies. Methods The intestinal nematode infection in population and contamination of eggs and hookworm larvae in soil were monitored and the epidemic factors evaluated 3 and 5 years after the mass chemotherapy in three pilot experimental villages in which intestinal nematodiasis was controlled with the mass chemotherapy. Results The overall infection rates of human intestinal nematodes in the villages in the Southern and the Middle Jiangsu, in which economical, cultural and health conditions were better, reduced continuously, while the overall and individual infection rates in pilot experimental villages in the Northern Jiangsu,in which conditions were worse, increased obviously. The change of contamination of eggs in soil was corresponded with those of infection rate in population. Conclusion The long-term efficacy of mass chemotherapy against intestinal nematodiasis is very different in different endemic areas. The economical, cultural and health conditions, and individual behaviors play an important role in consolidating the achievement of the diseases control.[