生物类黄酮化合物的结构与生物活性的关系

The relationship between chemical structure and bioactivity of bioflavonoids

概述了生物类黄酮化合物结构,并阐述了相应的生物活性。不同位置的不同基团的取代,有不同的生物活性,如抗氧化、抗肿瘤、抗HIV及与苯并二氮受体(BDZR)的亲合力,且相应活性强弱也不同;另外还介绍了7-羟基黄酮化合物的衍生物、黄酮金属络合物的生物活性等。

The relation between the biological activities of bioflavonoids and its corresponding compounds with dissimilar structure were reviewed.These compounds represented various properties due to the different substituents at the respective position,such as anti_oxidation,anti_tumour,anti_HIV and so on.