炎症反应器官功能不全评分评估危重病人病情的研究

Initial study of evaluating severity of critical illness by inflammatory response organ dysfunction score

目的探讨炎症反应器官功能不全评分(IRODS)在评估ICU病人病情和预后中的应用价值。方法应用新构建的IRODS回顾性地对ICU病人病情进行量化评分,考察IRODS在生存组和死亡组间的差异以及IRODS与ICU病死率的关系,比较该评分与APACHEII的评估效能。结果入院初始和24h的IRODS在生存组和死亡组间有显著性差异(P<0.001);随着IRODS增加,ICU病死率增加;入院初始及24hIRODS的接受者操纵特征曲线下面积(AUROCC)分别是0.930和0.934,APACHEII的AUROCC是0.956,两者间无显著性差异(P>0.05)。结论在入院初期,IRODS可用于评估危重病人的病情和预后,与APACHEII有相近的评估效能,但更为简便。

Objective To investigate the clinical value of inflammatory response organ dysfunction score (IRODS) in evaluating the patients in ICU. Methods A new IRODS was used to evaluate retrospectively the patients in the ICU, detect the difference of IRODS between survivors and non-survivors, observe the relationship between IRODS and the ICU mortality rate and compare evaluation effect between IRODS and APACHEⅡ. Results There was the significant difference in IRODS between survivors and non-survivors at initial time point and the 24th hour time point(P<0.001); the ICU mortality rate rose with IRODS increasing; the AUROCC of the IRODS at the initial time point and at the 24th hour respectively was 0.930 and 0.934 and the AUROCC of APACHEⅡ was 0.956, no statistical significance was found among them. Conclusion IRODS can be applied at the early stage of admitting to ICU. IRODS and APACHEⅡ have the same evaluation effect, but IRODS is easier. [