高压氧治疗重度颅脑损伤及脑出血术后患者的多重影响因素

Analysis of multifarious factors on the treatment of hyperbaric oxygen for patients with severe craniocerebral injury and cerebral hemorrhage

目的:探讨重度颅脑损伤及脑出血术后患者高压氧治疗和其他多项与治疗相关的影响因素。方法:采用回顾性方法对首都医科大学附属北京朝阳医院高压氧科1998-01/2003-12收治的重度颅脑损伤及脑出血术后患者多种影响因素进行分析,用秩和检验的方法对高压氧治疗患者的疗效、神经功能缺损评分改善情况、意识程度改善情况进行高压氧治疗前后的对比分析。结果:高压氧治疗20次患者神经功能缺损程度评分和意识状态较高压氧治疗10次疗效好(u=9.0134,P<0.01)。结论:了解重症颅脑损伤患者病情、治疗策略、方法及其与此相关的社会人文环境的思考,对患者最大限度的功能恢复具有重要意义。

AIM: To study multifarious factors on treatment of hyperbaric oxygen (HBO) and other correlative factors in patients with severe craniocerebral injury and cerebral hemorrhage. METHODS: Totally 187 patients with severe craniocerebral injury and cerebral hemorrhage in the Department of Hyperbaric Oxygen,Beijing Chaoyang Hospital of Capital University of Medical Science, from January 1998 to December 2003 were observed. A retrospective study was performed to evaluate the multifarious factors of HBO patients. The effect, amelioration of neurologic impairment and glasgow coma scale of patients were analyzed with rank sum test before and after HBO therapy. RESULTS: The scores on neurological impairment and consciousness were improved more significantly in patients with twenty time HBO treatment than those with ten time HBO treatment(u=9.013 4,P< 0.01). CONCLUSION: It is very important to comprehend the condition, therapy strategy, methods and the relative thinking of social and humanistic environment in patients with severe craniocerebral injury patient. There are important significances for the functional recover of patients to the maximum degree.