摘要
目的观察糖脉安泰(黄芪、肉桂等)对糖尿病肾病大鼠血脂及肾功能的影响。方法用链脲佐菌素复制糖尿病肾病大鼠模型,观察糖脉安泰口服液对其空腹血糖、血胆固醇、甘油三脂及血肌酐、尿素氮、尿蛋白的影响。结果糖脉安泰口服液各组可降低大鼠血胆固醇、甘油三脂、血肌酐、尿素氮、尿蛋白等,与模型组比较有显著性差异(P<0.05),以中剂量组疗效最佳。结论糖脉安泰口服液可以降低实验性糖尿病肾病大鼠血胆固醇与甘油三脂水平,改善肾功能。
AIM: To observe the effect of Tangmaiantai on the plasma lipid and renal function of rat with diabetic nephropathy. METHODS: The rat model of diabetic nephropathy was established by using STZ. The effect of Tangmaiantai on rat blood glucose before meal, serum TC, TG, Ccr, BUN and urinary protein were observed. RESULTS: Tangmainantai could decrease the level of serum TC, TG, Ccr, BUN and urinary protein, comparing to that of the model group (P<0.05) remarkably. Especially the middle-dose group had the best effect. CONCLUSION: Tangmaiantai can decrease the level of serum TC and TG, and improve renal function of the experimental diabetic nephropathy rat.
出处
《中成药》
CAS
CSCD
北大核心
2005年第1期62-64,共3页
Chinese Traditional Patent Medicine
