妊娠期肝内胆汁淤积症患者的新生儿脐动脉血气分析

Analysis of Neonatal Umbilical Artery Blood Gases of ICP Cases

【目的】探讨妊娠期肝内胆汁淤积症 (ICP)患者的新生儿脐动脉血气的特点及缺氧、酸中毒的情况。【方法】观察组 35例为ICP患者之新生儿 ,对照组 14 2例为正常孕妇分娩的新生儿。检测两组脐动脉血气指标 (pH、BE、PO2 、PCO2 )。【结果】观察组pH为 7.2 0± 0 .16、BE为 - 8.95± 0 .6 0 ,对照组 pH为 7.2 6± 0 .0 7、BE为 - 6 .76± 0 .0 3。两组间 pH、BE比较差异均有显著性 (P <0 .0 1和P <0 .0 5 )。【结论】ICP患者的新生儿脐动脉血 pH、BE均降低 ,新生儿出生时存在缺氧、酸中毒 ,因此对ICP患者孕期应积极处理 ,适时终止妊娠 ,放宽剖宫产指征 ;其新生儿应常规行脐动脉血气分析 ,早期发现问题 ,及时处理。

To analyse the results of ICP neonatal umbilical artery blood gases and study neonate hypoxia and acidosis.Neonatal blood gases (pH?BE?PO 2?PCO 2) of 35 cases ICP (study group) and 142 neonates of normal pregnancy(control group) were measured.pH,BE in the study group were 7.26±0.16 ,-8.95±0.60, respectively,while those in the control group were 7.26±0.07 , -6.76±0.03, respectively, there were significant differences in pH,BE(P<0.001,P<0.05), respectively.[Conclusion]pH and BE of ICP neonates decrease. The neonate shows symptoms of oxygen deficit and acidosis,so ICP should be effectively treated, pregnancy be terminated in time and cesarean section should be considered. A routine analysis of neonatal umbilical artery blood gases should be made and the neonate be treated as soon as possible.