急性视网膜坏死综合征的早期诊断与治疗

Early Diagnosis and Treatment of Acute Retinal Necrosis Syndrome

【目的】探讨急性视网膜坏死综合征的早期诊断和治疗方法。【方法】回顾性研究17例18只眼急 性视网膜坏死综合征患者的临床表现和治疗措施。【结果】13只眼玻璃体切割联合眼内硅油填充术,术后视 网膜复位11只眼(85%),手术治疗后视力提高者7只眼(54%)。早期大剂量无环鸟苷治疗后,单眼发病者未 发现对侧眼发病。【结论】尽早应用大剂量的抗病毒药物,结合预防性玻璃体切割术可提高急性视网膜坏死 综合征的治疗效果,同时减少了对侧眼的发病率。

ObjectiveTo investigate the early diagnosis and treatment of acute retinal necrosis syndrome(ARNS).The clinical manifestations and therapeutic measures in 17 patients (18 eyes) with ARNS were studied retrospectively.Thirteen eyes from ARNS patients were subjected to vitrectomy combined tamponade with silicone oil. After operation, retinal reattachment achieved in 11 eyes (85%) and vision improved in 7 eyes (54%).The opposite eyes in single-eye involved patients were not suffered from the attack of acute retinal necrosis following early sufficient dose of antiviral (acyclovir) therapy.[Conclusions]Earlier administration of antiviral drugs in large dose coordinated with prophylactic vitrectomy can improve the therapeutic efficacy of ARNS and simultaneously reduce the morbidity of opposite eyes.