异基因骨髓移植中巨细胞病毒的临床检测

Clinical Detection of CMV in Allogeneic Bone Marrow Transplantation——Review

在异基因骨髓移植中 ,巨细胞病毒 (CMV)感染常可引起致命危险及移植失败 ,因而探索早期准确检测CMV感染的有效实验手段至关重要。本文介绍了传统的CMV的培养法及近年来发展起来的抗原检测方法和分子生物学方法。

Human cytomegalovirus (CMV) infection may cause life threatening complications and lead to failure in transplantation. So, it is very important to explore the laboratory methods which can detect the CMV sufficiently early and accurately. This review discusses methodological aspects of quantitative CMV assays with emphasis on recently deve loped antigen detection assays and molecular biological methods.