胸腹水特异性IgM抗体在结核性胸腹水诊断中的意义

The Significance of Specific IgM Antibody in Pleural and Peritoneal Effusion of the Patients with Tuberculosis

用酶联免疫吸附试验测定70例胸腹水抗PPD-IgM抗体,并与抗PPD-IgG抗体作比较,两者敏感性分别为72.9％和92.5％,特异性为96.9％和84.8％。检测特异性IgM抗体有助于结核性胸腹膜炎的早期诊断。同时检测抗PPD-IgM和IgG抗体,再结合溶菌酶综合判断,为结核性胸腹水有价值的辅助诊断方法。

The anti-PPD IgM antibody in specimens of 70 pleural and peritoneal effusions was determined by ELISA and compared with anti-PPD IgG antibody. The sensitivity was 72.9% and 92.5%, the specificity 96.9% and 84.8%, respectively. The results suggested that determination of specific IgM antibody is helpful to early diagnosis of tuberculous pleurisy and peritonitis, and that the synthetic tests including specific IgM and IgG antibodies, together with LZM are valuable to adjuvant diagnosis of tuberculous pleurisy and peritonitis.