艾滋病相关机会感染的临床研究

Clinical Analysis and Management of Opportunistic Infections of Patients with AIDS

目的 总结艾滋病患者合并相关机会感染的发生情况和治疗经验。方法 对 5 1例艾滋病患者的临床资料进行分析 ,其中检测了 4 4例病人的CD4+ /CD8+ T细胞 ,对 33例病人进行高效抗逆转录病毒治疗 (HAART)。结果 艾滋病患者的机会感染以真菌感染最为常见 ,结核杆菌感染次之 ,病毒感染以疱疹病毒感染最常见。结论 对于青壮年并发真菌、结核杆菌、单纯疱疹病毒感染者 ,如不能用常规原因解释 ,应检查抗HIV以便尽早确诊。在HAART治疗的基础上 ,预防、诊断和治疗机会感染能明显降低死亡率和改善病人的预后。

Objective To study incidence of main opportunistic infections and therapy experiences of opportunistic infections of patients with AIDS. Methods 51 cases with AIDS were all in Shenzhen East Lake Hospital. Their clinical manifestations were summariaed, 44 cases were detected CD 4+/CD 8+ T cell count, 33 cases received highly active antiretroviral therapy(HAART).Results Fungal infections are the most common opportunistic infections of patients with AIDS,TB (tuberculosis) was the second. HPS(herpes simplex virus) infection was the most common viral opportunistic infections of patients with AIDS.Conclusions If adolescents and adults are infected with fungus、 tuberculosis or herpes simple virus which could not be explained with conventional reasons, these patients should be detected by antibody of HIV as soon as possible.Prophylaxis,diagnosis and HAART treatment of PCP, TB, HSV earlier can reduce the incidence and mortality of opportunistic infections and improve prognosis of AIDS.