咳嗽变异性哮喘110例临床分析

Clinical analysis in 110 cases of cough variance asthma

目的提高对咳嗽变异性哮喘(CVA)临床特点的认识。方法对110例CVA的临床表现、实验室检查、诊断及治疗资料进行回顾分析。结果110例CVA均以慢性咳嗽为主要症状,肺部听诊及胸片检查基本正常,部分患儿或家族有过敏史。48例CVA血MPIgM检测呈阳性,其中37例血IgE升高,示此48例系肺炎支原体感染后诱发的CVA。全组110例CVA确诊前曾用抗生素无效,经支气管舒张剂沙丁胺醇及吸入型糖皮质激素布地奈德雾化吸入治疗后,短期内咳嗽明显减轻或消失。结论肺炎支原体感染可能诱发CVA。临床医师应对CVA有足够的认识,避免误诊,做到早诊断、早治疗。

Objective To improve the knowledge for the clinical characteristics of cough variance asthma(CVA).Methods The clinical manifestation,laboratory examinations,diagnose and treatment data for 110 cases of CVA were analyzed retrospectively.Results All the 110 cases of CVA were based on the slow cough as the main symptom,their lung auscultation & chest card checks were basic normal,some sick children or family had the allergic history.48 cases of CVA MP-IgM checks were masculine,among them,37 cases blood IgE rised.It indicated that these 48 cases were the entrapped CVA after infecting the mycoplasma pneumonia.The whole set of 110 cases had used the antibiotic without effect before diagnosed,after by the bronchus diastolic agent shading amine-mellow and the suction-type sugar skin hormone budinade fog intake method,the cough during the short period was decreased obviously or disappeared.Conclusions The clinical doctor should know the CVA enough avoiding the erroneous diagnosis,and should diagnose it early and cure it early.Through some cases related data,the mycoplasma pneumonia infection may entrap the CVA.