1452株临床分离菌及常见菌药敏分析

Analysis of the resistance of 1 452 clincially isolated bacteria strains to antibiotics.

目的 了解延边地区临床分离菌的构成和对常规抗生素的敏感情况,为临床治疗提供依据。 方法 用常规法分离和鉴定细菌,以及K-B法测定细菌的药物敏感度。 结果 共分离1452株临床分离茵株,其中萄萄球菌在菌血症、尿路感染及伤口感染中所占比例较高;肠杆菌科细菌是肠道感染的主要致病茵。头孢拉啶、头孢哌酮和氨基糖甙类抗生素对葡萄球菌的抗菌作用很强,抗菌率超过70％;丁胺卡那、头孢噻肟、头孢哌酮对革兰氏阴性杆菌抑菌效果显著,抑菌率在70％以上。 结论 在延边地区的细菌感染中G-杆菌占主导地位,头孢噻肟和头孢哌酮对G+球菌和G-杆菌敏感率都较高。

Objective To understand the composition of clinical isolated bacterium strains and their sensitivity to conventional antibiotics in this area and provide scientific basis for clinical treatment of bacterium infection. Methods The infetious sites and proportion of 1 452 clinically isolated strains were analyzed and the susceptibility of bacteria to conventional antibiotics was detemined by using K-B method. Results Totally 1 452 strains of bacteria were isolated. The infectious rates of Staphy lococcus aureus in the infection of bacterimia,urnary tract infections and wounds were relatively higher.The enterobacteria is the main pathogenic bacterium in intestinal infections. The antibiotics of Cefazolin, Cefradine, Cefoperazone and aminoglycoside are effective against Staphylococcus aureus with a effective rate of over 70% . Amikacin, Cefotaxime and Cefoperazone show significant antibacterial effect with an effective rate of over 70% . Conclusion G- bactria still predominate in hospital infection in this area both G- and G+ bacteria are sensitive to the antibiotics of Cefotaxine and Cefoperazone.