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选择性醛固酮受体拮抗药依普利酮及其临床应用进展 被引量:1

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出处 《首都医药》 2005年第3期31-33,共3页 Capital Medicine
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  • 1Davis KL, Nappi JM.The cardiovascular effects of eplerenone,a selective aldosteronereceptor antagonist. Clinical Therapeutics.2003,25(11): 2647~2668
  • 2Rudolph AE,Rocha R,McMahon EG.Aldosterone target organ protection by eplerenone. Mo 1.Cell. Endocrinol.2004,217:229~238
  • 3Davis KL, Nappi JM.The cardiovascular effects of eplerenone ,a selective aldosteronereceptor antagonist. Clin. Ther.2003,25:2647 ~2668
  • 4de Paula RB, da Silva AA, Hall JE.Aldosterone Antagonism Attenuates Obesity-Induced ltypertension and glomerular Ltyperfiltration.Hypertension.2004,43: 41~47
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  • 6Black HR.Evolving role of aldosterone blockers alone and in combination with angiotensin-converting enzyme inhibitors or angiotensin. A receptor blockers in hypertension management:A review of mechanistic and clinical data. Am Heart J 2004,147:564~572
  • 7Funder JW.The role of mineralocorticoid receptor antagonists in the treatment of cardiac failure. Expert Opin. Investig. Drugs 2003,12(12): 1963~1969
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同被引文献8

  • 1Delyani JA,Rocha R,Cook CS,et al.Eplerenone:a selective aldosterone receptor antagonist (SARA).Cardiovasc Drug Rev,2001,19(3):185-200
  • 2Rocha R,Williams GH.Rationale for the use of aldosterone antagonists in congestive heart failure.Drugs,2002,62(5):723-731
  • 3Hayashi M,Tsutamoto T,Wada A,et al.Immediate administration of mineralocorticoid receptor antagonist spironolactone prevents post-infarct left ventricular remodeling associated with suppression of a marker of myocardial collagen synthesis in patients with first anterior acute myocardial infarction.Circulation,2003,107(20):2559-2565
  • 4Bauersachs J,Heck M,Fraccarollo D,et al.Addition of spironolactone to angiotensin-converting enzyme inhibition in heart failure improves endothelial vasomotor dysfunction:role of vascular superoxide anion formation and endothelial nitric oxide synthase expression.J Am Coll Cardiol,2002,39(2):351-358
  • 5Pitt B,Zannad F,Remme WJ,et al.The effect of spironolactone on morbidity and mortality in patients with severe heart failure.N Engl J Med,1999,341(10):709-717
  • 6Pitt B,Remme W,Zannad F,et al.Eplerenone,a selective aldosterone blocker,in patients with left ventricular dysfunction after myocardial infarction.N Engl J Med,2003,348(14):1309-1321
  • 7Cicoira M,Zanolla L,Rossi A,et al.Long-term,dose-dependent effects of spironolactone on left ventricular function and exercise tolerance in patients with chronic heart failure.J Am Coll Cardiol,2002,40(2):304-310
  • 8李延辉 那开宪.慢性心力衰竭的历史、现状和未来.中华临床杂志,2003,3(4):53-59.

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