期刊文献+

趋化因子与慢性丙型肝炎 被引量:1

下载PDF
导出
摘要 越来越多的实验证实,慢性丙型肝炎(chronic hepatitis C, CHC)患者肝脏局部炎症产生的趋化因子(chemokines,CK) 在淋巴细胞的迁移和募集中起着至关重要的作用,他不仅与肝细胞损伤程度密切相关,可能是肝病加重的潜在预兆, 而且与干扰素治疗后的应答反应密切相关.因此,本文就趋化因子的分类、分泌细胞、趋化细胞的类型,趋化因子与慢性HCV感染肝脏炎症程度的关系以及趋化因子对慢性HCV感染干扰素治疗应答的影响等进行了简要的综述.
出处 《世界华人消化杂志》 CAS 2004年第11期2664-2667,共4页 World Chinese Journal of Digestology
  • 相关文献

参考文献5

二级参考文献72

  • 1Sheron N, Bird G, Koskinas J, Portmann B, Ceska M, Lindley I, Williams R. Circulating and tissue levels of the neutrophil chemotaxin interleukin-8 are elevated in severe acute alco-holic hepatitis, and tissue levels correlate with neutrophilinfiltration. Hepatology 1993;18:41-46.
  • 2Hill DB, Marsano LS, McClain CJ. Increased plasma interleukin-8 concentrations in alcoholic hepatitis. Hepatology 1993;18:576-580.
  • 3Huang YS, Chan CY, Wu JC, Pai CH, Chao Y, Lee SD. Serum levels of interleukin-8 in alcoholic liver disease: relationship with disease stage, biochemical parameters and survival. J Hepatol 1996;24:377-384.
  • 4Shiratori Y, Takada H, Hikiba Y, Nakata R, Okano K, Komatsu Y, Niwa Y, Matsumura M, Shiina S, Omata M, Kamii K.Production of chemotactic factor, interleukin-8, from hepatocytes exposed to ethanol. Hepatology 1993;18:1477-1482.
  • 5Nanji AA, Jokelainen K, Rahemtulla A, Miao L, Fogt F,Matsumoto H, Tahan SR, Su GL. Activation of nuclear factor kappa B and cytokine imbalance in experimental alcoholicliver disease in the rat. Hepatology 1999; 30:934-943.
  • 6Kharbanda KK, Todero SL, Shubert KA, Sorrell MF, Tuma DJ.Malondialdehyde-acetaldehyde protein adducts increase secretion of chemokines by rat hepatic stellate cells. Alcohol 2001;25:123-128.
  • 7Afford SC, Fisher NC, Neil DA, Fear J, Brun P, Hubscher SG,Adams DH. Distinct patterns of chemokine expression are associated with leukocyte recruitment in alcoholic hepatitis and alcoholic cirrhosis. J Pathol 1998;186:82-89.
  • 8Maher JJ, Scott MK, Saito JM, Burton MC. Adenovirus-medi-ated expression of cytokine-induced neutrophil chemoattractant in rat liver induces a neutrophilic hepatitis. Hepatology 1997;25:624-630.
  • 9Maltby J, Wright S, Bird G, Sheron N. Chemokine levels in human liver homogenates: associations between GRO alpha and histopathological evidence of alcoholic hepatitis.Hepatology 1996;24:1156-1160.
  • 10Fisher NC, Neil DA, Williams A, Adams DH. Serum concentrations and peripheral secretion of the beta chemokines monocyte chemoattractant protein 1 and macrophage inflammatory protein 1 alpha in alcoholic liver disease. Gut 1999;45:416-420.

共引文献70

同被引文献6

引证文献1

二级引证文献5

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部