糖尿病并脑梗死的发病和预后及与血脂的关系

Relationship between the Blood Lipid Level and Prognosis in Diabetic Patients Complicated with Cerebral Infarction

目的 探讨 60例糖尿病并经CT证实脑梗死患者的血糖、血脂与其梗塞灶最大直径、神经功能损伤、临床疗效、并发症和死亡率的关系。方法 60例糖尿病并脑梗死与 60例非糖尿病脑梗死进行比较 ,大灶梗死亚组与小灶梗死亚组血脂比较。结果 糖尿病并脑梗死时多为主干支大灶性梗死 ,且神经功能损伤重 ,临床疗效差 ,并发症和死亡率高。另外脑梗死面积、并发症和死亡率均与血糖、血脂水平呈正相关。结论 血糖和血脂水平升高可加重脑梗死损害 ,应积极控制血糖和血脂。

Objective To explore the relationship among the level of blood glucose and lipid, the cerebral infarction(CI) size, neurological deficits, efficacy, complications and mortality in diabetic patients complicated with cerebral infarction. Methods The clinical data of 60 diabetic patients complicated with cerebral infarction were compared with those of 60 cerebral infarction patients with normoglycemia. Results Compared with cerebral infarction of patients with normoglycemia, that of diabetic patients occurred in the main artery branch, who had larger infarct size, more neurological deficits,worse efficacy,more complications and higher mortality. The frequency of complications and mortality were positively related with the level of glycemia and blood lipid in the diabetic patients complicated with cerebral infarction. Conclusion Hyperglycemia and hyperlipemia could aggravate the brain damage in diabetic patients complicated with cerebral infarction. Controlling hyperglycemia and hyperlipemia was beneficial to the prognosis of cerebral infarction.