围产期血浆DLIS水平的动态观察

A STUDY ON THE PLASME LEVELS OF DLIS IN PARTURIENTS

本文检测了15例正常产妇产前、产时及产后血浆地高辛样免疫活性物质(DLIS)的水平。结果产前与非孕期健康对照组相比无显著性差别,产时及产后即刻较临产前明显升高(p<0.01),而产后24小时已降至产前水平。推测产时母体血浆DLIS水平的升高可能与产痛等应激因素有关;产后即刻的高水平可能是产时的延续或/和大量子宫血液进入母体循环使心脏负荷加重有关,提示产时及产后24小时内血浆DLIS水平的监测对了解产妇的应激程度和心脏负荷情况具有一定的指导意义。

The plasma levels of Digoxin-like immunoreactive Substanse(s) (DLIS) in 15 normal parturients were measured with radio immunoassay in antepartum, intrapartum and postpartum. The results showed that there were no significantdifference between the levels in antepartum and those of nonpregnancy women, but its concentrations in intrapartum and immediate postpartum were significantly higher (P<0.01) than those in antepartum. At the 24th-h0ur in postpartum, the levels had decreased to those of antepartum. It is postulated that the elevation of DLIS during labor is in relation with the stress, and that the elevation in immediate postpartum is caused by the large amount of blood of uterine entering maternal circulation. The results suggest that to monitor the levels of DLIS during labor and in 24 hours of postpartum may have some values to know the level of stress of parturinents and the loading state of their hearts.