2Ziegler A, Zangemeister-Wittke U, Stahel RA. Circulating DNA :a new diagnostic gold mine? [ J ]. Cancer Treat Rev, 2002,28(5) :255 -271.
3Silva JM, Garcia JM, Dominguez G, et al. Persistence of tumor DNA in plasma of breast cancer patients after mastectomy [ J ].Ann Surg Oncol, 2002,9( 1 ) :71 -76.
4Silva JM ,Silva J ,Sanchez A,et al. Tumor DNA in plasma at diagnosis of breast cancer patients is a valuable predictor of diseaseree survival[ J]. Clin Cancer Res, 2002,8 ( 12 ) :3761 - 3766.
5Wang BG, Huang HY, Chen YC, et al, Increased plasma DNA integrity in cancer patients [ J ]. Cancer Res, 2003,63 : 3966 -3968.
6Gastells A,Puig P, Mora J,et al. K-ras mutations in DNA extracted from the plasma of patients with pancreatic carcinoma: diagnostic utility and prognostic significance[J]. J Clin Oncol, 1999,17(2) :578 -584.
7Kopreski MS, Benko FA, Borys D J, et al. Somatic mutation screening: identification of individuals harboring K-ras mutations with the use of plasma DNA [ J ]. J Natl Cancer Inst, 2000,92(11) :918 -923.
8Shao ZM, Wu J,Shen ZZ,et al. p53 mutation in plasma DNA and its prognostic value in bresat cancer patients [ J ]. Clin Cancer Res, 2001,7 ( 8 ) :2222 - 2227.
9Kirk GD, Gamus-Randon AM, Mendy M. Ser-249 p53 mutations in plasma DNA of patients with hepatocellular carcinoma from the Gambia[ J]. J Natl Cancer Inst, 2000,92(2) :148 - 153.
10Usadel H, Brabender J, Danenberg KD. Quantitative adenomatous polyposis coil promoter methylatlon analysis in tumor tissue, serum,and plasma DNA of patients with lung cancer [ J]. Cancer Res, 2002,62 ( 2 ) :371 - 375.
二级参考文献7
1Kok K,Naylor SL,Buys CH.Deletions of the short arm of chromosome 3 in solid tumors and the search for suppressor genes[].Advances in Cancer Research.1997
2Fullwood P,Marchini S,Rader JS,et al.Detailed genetic and physical mapping of tumor suppressor loci on chromosome 3p in ovarian cancer[].Cancer Research.1999
3Chen XQ,Stroun M,Magnenat JK,et al.Microsatellite alterations in plasma DNA of small cell lung cancer patients[].Nature Medicine.1996
4Goessl C,Heicappell R,Munker R,et al.Microsatellite analysis of plasma DNA from patients with clear cell renal carcinoma[].Cancer Research.1998
5Hickey KP,Boyle KP,Jepps HM,et al.Molecular detection of tumor DNA in serum and peritoneal fluid from ovarian cancer patients[].British Journal of Cancer.1999
6Nawroz H,Koch W,Anker P,et al.Microsatellite alterations in serum DNA of head and neck cancer patients[].Nature Medicine.1996
7Fujiwara Y,Chi DD,Wang HJ,et al.Plasma DNA microsatellite as tumor-specific markers and indicators of tumor progression in melanoma patients[].Cancer Research.1999